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Low-Grade Chronic Inflammation

"The Secret Killer"

Low-Grade Chronic Inflammation is a silent condition that goes unnoticed and can kill. A strong immune system helps fight viruses and bacteria. For this reason we devised an anti-inflammaging ecosystem which will distance people from diseases generated by inflammation and premature ageing.

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It is linked to COVID-19 severity* cases

It is the major cause of premature

deaths globally**

Research of the past two decades led to the

discovery that low-grade inflammation is the common soil of many diseases and, thus, at the root of many deaths. Through its reduction of immune fitness, low-grade inflammation is also believed to be instrumental in the development of severe COVID-19 cases.

Accelerates aging

Low-Grade Inflammation increases with aging, which is why the term inflammaging was coined about 20 years ago. Inflammaging goes not only along with an increased risk for many diseases, but also with frailty and cognitive decline. All together accelerates aging.

Known mechanisms

The research has moved beyond the level of merely associating the silent inflammation with many diseases and conditions. We now also know its  molecular origin: the NLRP3 inflammasome. The activation of this inflammasome starts a molecular cascade affecting virtually all organs.

Chronic and not perceivable

In contrast to the beneficial acute inflammation that repairs and heals injuries and comes to a stop after having done its job, low-grade inflammation is not resolved. Unless counteracting measures are undertaken, the inflammation remains chronic and can act for decades - without becoming noticeable.

Image by Anna Pelzer

Examples of factors
influencing Low-Grade Chronic Inflammation

Stress relief at the workplace

Regular exercise in elderly people

Mediterranean diet

Air pollution exposure

Current cigarettes smokers